The Effect of Aurovertin on a Soluble Mitochondrial Adenosine Triphosphatase

作者：Anthony M. Roberton, R. BRIAN BEECHEY, Caroline Tobia Holloway, I. G. Knight · 发表于：Biochemical Journal · 年份：1967 · DOI：10.1042/bj1040054c · 被引用次数：57 · 研究领域：Bioactive Compounds and Antitumor Agents、Marine Sponges and Natural Products、Antioxidant Activity and Oxidative Stress

effect by added deoxyribonucleosides. Alterna- tively, it has been postulated that the added deoxyribonucleosides are so rapidly cleaved to free bases as to be only partially effective in blocking the hydroxyurea effect (Young et al. 1967a).It seems unlikely, however, that all of the added deoxy- ribonucleoside was cleaved to the free base form, since the animals receiving the four deoxyribo- nucleosides but not hydroxyurea clearly showed a stimulation of the incorporation of phosphate into DNA that was significantly different from control values.