Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan

作者：Yoav Keynan, Oscar Larios, Marni Wiseman, Marie Plourde, Marc Ouellette, Ethan Rubinstein · 发表于：Canadian Journal of Infectious Diseases and Medical Microbiology · 年份：2008 · DOI：10.1155/2008/802710 · 被引用次数：37 · 研究领域：Research on Leishmaniasis Studies

Old world cutaneous leishmaniasis (CL) is caused by Leishmania major and Leishmania tropica, and is endemic to several Asian and Middle-Eastern countries where the rates of infection can be substantial. CL is one of the most common vector-transmitted parasitic infections in Afghanistan. Six cases of CL in Canadian soldiers returning from Afghanistan are reported in the present study. Their lesions did not improve with fluconazole therapy, and the organism demonstrated in vitro resistance. Oral miltefosine seemed effective.