Effective Chemical Inactivation of Ebola Virus

作者：Elaine Haddock, Friederike Feldmann, Heinz Feldmann · 发表于：Emerging infectious diseases · 年份：2016 · DOI：10.3201/eid2207.160233 · 被引用次数：108 · 研究领域：Viral Infections and Outbreaks Research、Viral Infections and Vectors、Viral gastroenteritis research and epidemiology

Reliable inactivation of specimens before removal from high-level biocontainment is crucial for safe operation. To evaluate efficacy of methods of chemical inactivation, we compared in vitro and in vivo approaches using Ebola virus as a surrogate pathogen. Consequently, we have established parameters and protocols leading to reliable and effective inactivation.