A new Secondary metabolites of the crinoid (Comanthina schlegeli) associated fungus Alternaria brassicae 93

作者：Liuhong Zhang, Hongwei Wang, Jiayi Xu, Jing Li, Lan Liu · 发表于：Natural Product Research · 年份：2016 · DOI：10.1080/14786419.2016.1166498 · 被引用次数：19 · 研究领域：Microbial Natural Products and Biosynthesis、Mycotoxins in Agriculture and Food、Fungal Plant Pathogen Control

Fungus Alternaria brassicae 93 isolated from crinoid (Comanthina schlegeli), which was collected from the South China Sea. Six compounds were isolated from A. brassicae 93, including one new compound (1), along with five known compounds, ochratoxin A methyl ester (2), cis-4-hydroxym-ellein (3), (R)-7-hydroxymellein (4), trans-2-anhydromevalonic (5) and protocatechuic acid (6). Their structures were determined by spectroscopic methods and comparison with reported data. Cytotoxicity against two human cancer cell lines and antibacterial activity against twelve aquatic bacteria of compound 1 were also tested.