Histochemical Demonstration of Sites of Choline Esterase Activity.

作者：George Gömöri · 发表于：Experimental Biology and Medicine · 年份：1948 · DOI：10.3181/00379727-68-16485 · 被引用次数：146 · 研究领域：Medical and Biological Sciences、Plant-based Medicinal Research、Neurological Disorders and Treatments

Some choline esterases hydrolyze higher choline esters readily and they also survive to a demonstrable extent the procedures of histological fixation and embedding. It is possible to demonstrate them histo-chemically by incubating slides with the substrate in the presence of a cobalt salt; at the sites of choline esterase activity insoluble cobalt-soap will precipitate which can be transformed into black CoS. The histochemical distribution and properties of choline esterase are described.