Further Observations on Addiction to Methadon in the Monkey.

作者：Joseph Cochin, Carl C. Gruhzit, L.A. Woods, Maurice H. Seevers · 发表于：Experimental Biology and Medicine · 年份：1948 · DOI：10.3181/00379727-69-16743 · 被引用次数：8 · 研究领域：Neurotransmitter Receptor Influence on Behavior、Diet and metabolism studies、Stress Responses and Cortisol

Racemic methadon administered thrice daily in maximal tolerated dose, does not induce a significant degree of physical dependence in the monkey (Macaca mulatta) confirming previous experiments involving single daily administration.