Synthesis of Functionalized Chromeno[2,3- b ]pyrrol-4(1 H )-ones by Silver-Catalyzed Cascade Reactions of Chromones/Thiochromones and Isocyanoacetates

作者：Xueyu Qi, Hao‐Yue Xiang, Chunhao Yang · 发表于：Organic Letters · 年份：2015 · DOI：10.1021/acs.orglett.5b02795 · 被引用次数：50 · 研究领域：Synthesis of Organic Compounds、Oxidative Organic Chemistry Reactions、Multicomponent Synthesis of Heterocycles

A novel and convenient approach to the synthesis of chromeno[2,3-b]pyrrol-4(1H)-ones has been developed. Furthermore, the method involves a facile silver-catalyzed cascade cyclization reaction including an intramolecular C-O bond formation. The silver salt acts as a key promoter.