Studies on the Role of the Family Unit in the Transmission of Trachoma

作者：Joan E. Barenfanger · 发表于：American Journal of Tropical Medicine and Hygiene · 年份：1975 · DOI：10.4269/ajtmh.1975.24.509 · 被引用次数：30 · 研究领域：Reproductive tract infections research、Immune Response and Inflammation、Antimicrobial Peptides and Activities

Rates of trachoma infection of family members were compared for two groups of index cases; all were infants about 1 year old observed over a period of several months in a previous study. Group A infants were consistently infected with trachoma, and Group B infants were not infected with trachoma. On the average, 50% of Group A family members had active infection (as determined by trachoma inclusions in their conjunctival cells) and 80% of the siblings within 6 years of age to the index cases were infected. Only 9% of Group B family members had active trachoma, and 20% of the siblings within 6 years of age to the index case were infected. This study suggests intrafamilial spread of trachoma.