Evidences for Circadian Rhythmicity in the per° Mutant of Drosophila melanogaster

作者：Charlotte Helfrich, Wolfgang Engelmann · 发表于：Zeitschrift für Naturforschung C · 年份：1987 · DOI：10.1515/znc-1987-11-1231 · 被引用次数：47 · 研究领域：Circadian rhythm and melatonin、Neurobiology and Insect Physiology Research、Light effects on plants

per0 Mutants of Drosophila melanogaster which are exposed to light-dark cycles (LD) with different Zeitgeber period (T) have a limited range of entrainment. Entrained flies show a characteristic phase relationship of activity to the LD which depends on the period of the driving cycle as expected by oscillator theory. Both facts are taken as evidence that per. possesses endogenous oscillators and that the per gene product is not concerned with central clock structures but rather might be responsible for the mutual coupling between the individual oscillators in a multioscillatory system controlling locomotor activity.