[Incidence and risk factors on HIV infection among injection drug users in Dehong prefecture area of Yunnan province].

作者：Song Duan, Li-fen Xiang, Yuecheng Yang, Runhua Ye, Manhong Jia, Hong-bing Luo, Liru Fu, Lijun Song, Yuxian Zhao, Jian-hua Yang, Bin Wang, Zhiyuan Liu, Yong-cheng Pu, Wenxiang Han, Zhong-jie Yang, Wei-mei Li, Jibao Wang, Weiming Zhu, Na He · 发表于：PubMed · 年份：2009 · 被引用次数：10 · 研究领域：Medicine、Demography、Internal medicine、Immunology、Sociology、Physics、Optics

OBJECTIVE: To determine the incidence and risk factors on HIV infection among injection drug users (IDU) in Dehong prefecture area of Yunnan province. METHODS: An epidemiological cohort of HIV-negative IDU had been developed and followed since October, 2004. HIV new infections and related behaviors had been investigated every six months. RESULTS: By the end of 2008, 760 HIV-negative IDU had been recruited and followed for a total of 1153.6 person-years. 47 new HIV infections were identified, with an overall incidence of 4.07/100 person-years during the follow-up period. The HIV incidence was 4.45/100 person-years during 2004 - 2006, 4.50/100 person-years in 2007 and 2.54/100 person-years in 2008. Both the behavior of drug injection and the HIV incidence among the cohort had substantially decreased during the follow-up period. Multiple regression analysis using Cox proportional hazard model indicated that people with Jing-po ethnicity (Hazard ratio, HR = 2.56, 95%CI: 1.06 - 6.19) and other minorities except for Dai (HR = 3.26, 95%CI: 0.89 - 11.96) were at higher risk for HIV infection than the people with Han ethnicity. People injecting drugs with (HR = 2.27, 95%CI: 0.98 - 5.25) or without (HR = 5.27, 95%CI: 2.25 - 12.34) needle sharing were at higher risk for HIV infection than those reporting having no drug injection behavior during the follow-up period. CONCLUSION: Both the behavior of drug injection and the HIV incidence among former IDU in Dehong prefecture area of Yunnan...