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Formation of Solid Human Mammary Carcinoma In Vitro

作者:Richard A. Knazek, Marc E. Lippman, Harish C. Chopra · 发表于:JNCI Journal of the National Cancer Institute · 年份:1977 · DOI:10.1093/jnci/58.2.419 · 被引用次数:17 · 研究领域:Cancer Cells and Metastasis

An established line of human breast carcinoma, MCF-7, when cultured within the artificial capillary system, formed solid masses of tissue. Acinar and ductular patterns developed, having the ultrastructural appearance of breast tissue that responds to exogenous hormones.