Ice-Binding Proteins and Their Function

作者：Maya Bar Dolev, Ido Braslavsky, Peter L. Davies · 发表于：Annual Review of Biochemistry · 年份：2016 · DOI：10.1146/annurev-biochem-060815-014546 · 被引用次数：437 · 研究领域：Physiological and biochemical adaptations、nanoparticles nucleation surface interactions、Insect and Arachnid Ecology and Behavior

Ice-binding proteins (IBPs) are a diverse class of proteins that assist organism survival in the presence of ice in cold climates. They have different origins in many organisms, including bacteria, fungi, algae, diatoms, plants, insects, and fish. This review covers the gamut of IBP structures and functions and the common features they use to bind ice. We discuss mechanisms by which IBPs adsorb to ice and interfere with its growth, evidence for their irreversible association with ice, and methods for enhancing the activity of IBPs. The applications of IBPs in the food industry, in cryopreservation, and in other technologies are vast, and we chart out some possibilities.