Overview of Microbial Therapeutic Enzymes

作者：Prajakta Mane, Vidya Tale, Rajiv Gandhi · 年份：2015 · 被引用次数：32 · 研究领域：Enzyme Production and Characterization、Enzyme Catalysis and Immobilization、Biochemical and Molecular Research

A B S T R A C T Enzymes possess specificity, greater affinity, and high catalytic efficiency. They are required for many chemical inter conversions that support life and speed up all the metabolic processes. These entire characteristics discern them from all other types of drugs. Due to these, enzymes are widely been used for different therapeutic purposes and enzyme therapies are acquiring much attention. Both digestive and metabolic enzymes can be used either separately or in combination with other therapies for the treatment of several diseases such as leukemia, skin ulcers, Pompe s disease, cardiovascular diseases, celiac disease, Parkinson s disease, Fabry s disease, inflammation, digestive disorders, pancreatic disorders etc. They are also employed in diagnosis, biochemical investigation and monitoring of many alarming diseases. Medically important enzymes produced by microorganisms have advantage of being economically feasible and consistent. They have high yield and are easy for product modification and optimization. The present review compiles the information on the sources and application of medically important enzymes produced by microorganisms and future prospects of these enzymes as drugs. K e y w o r d s Enzymes, Therapeutic, Digestive, Metabolic, Drugs