Complete solution of the three-compartment model in steady state after single injection of radioactive tracer

作者：S. M. Skinner, Richard E. Clark, N. Baker, Reginald A. Shipley · 发表于：American Journal of Physiology-Legacy Content · 年份：1959 · DOI：10.1152/ajplegacy.1959.196.2.238 · 被引用次数：95 · 研究领域：Radioactive element chemistry and processing、Nuclear reactor physics and engineering、Field-Flow Fractionation Techniques

Solutions of a general, three-compartment model in a nonisotopic steady state are developed. By means of these solutions, the investigator may analyze a great variety of kinetic flow relationships utilizing only algebraic procedures. Values of compartment sizes, rates of transport and specific activity-time curves are obtained for three typical hypothetical examples. Possible degrees of freedom and the use of parameters are examined. For those models where physical limitations prevent sufficient independent observations to allow completely determinate solutions, possible limiting values are established.