Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat

作者：Luis Antonio Castaño, George S. Eisenbarth · 发表于：Annual Review of Immunology · 年份：1990 · DOI：10.1146/annurev.iy.08.040190.003243 · 被引用次数：647 · 研究领域：Diabetes and associated disorders、Pancreatic function and diabetes、Diabetes Management and Research

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More