Transmission of Signals from the T Lymphocyte Antigen Receptor to the Genes Responsible for Cell Proliferation and Immune Function: The Missing Link

作者：Katharine S. Ullman, Jeffrey P. Northrop, C L Verweij, Gerald R. Crabtree · 发表于：Annual Review of Immunology · 年份：1990 · DOI：10.1146/annurev.iy.08.040190.002225 · 被引用次数：513 · 研究领域：Immune Cell Function and Interaction、T-cell and B-cell Immunology、T-cell and Retrovirus Studies

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More