Synthesis of 4′-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2′,5′-diphenyl-2′,4′-dihydro spiro[indolin-3,3′[1,2,4]triazol]-2-one derivatives

作者：Atiye Bazian, Milad Taheri, Haniyeh Alavi · 发表于：Russian Journal of General Chemistry · 年份：2014 · DOI：10.1134/s107036321403030x · 被引用次数：15 · 研究领域：Click Chemistry and Applications、Synthesis and biological activity、Synthesis and Biological Evaluation

In this paper 1,3-dipolar cycloaddition reaction has been studied. An efficient synthesis of 4′-[3-methyl-5-thioxo-1 H -1,2,4-triazol-4(5H)-yl]-2′,5′-diphenyl-2′,4′-dihydro spiro(indolin-3,3′[1,2,4]triazol)-2-one derivatives using triethylamine in MeCN at room temperature is reported. The structures of the obtained compounds were confirmed by means of elemental analysis, MS and spectral (IR, 1 H, and 13 C NMR) methods.