Time course EPI of human brain function during task activation

作者：Peter A. Bandettini, Eric C. Wong, R. Scott Hinks, Ronald S. Tikofsky, James S. Hyde · 发表于：Magnetic Resonance in Medicine · 年份：1992 · DOI：10.1002/mrm.1910250220 · 被引用次数：1959 · 研究领域：Advanced MRI Techniques and Applications、Advanced Neuroimaging Techniques and Applications、NMR spectroscopy and applications

Using gradient-echo echo-planar MRI, a local signal increase of 4.3 +/- 0.3% is observed in the human brain during task activation, suggesting a local decrease in blood deoxyhemoglobin concentration and an increase in blood oxygenation. Images highlighting areas of signal enhancement temporally correlated to the task are created.