Microbes, immunoregulation, and the gut: Figure 1

作者：G.A.W. Rook, L R Brunet · 发表于：Gut · 年份：2005 · DOI：10.1136/gut.2004.053785 · 被引用次数：340 · 研究领域：Probiotics and Fermented Foods、Gut microbiota and health、Pediatric health and respiratory diseases

Two distinct, but rapidly converging, areas of research (the hygiene hypothesis and the study of probiotic/prebiotic effects) have emphasised the need to understand, and ultimately to manipulate, our physiological interactions with commensal flora, and with other transient but harmless organisms from the environment that affect immunoregulatory circuits. The story began with allergic disorders but now inflammatory bowel disease is increasingly involved.