Fertility- and Menopause-Related Information Needs of Younger Women With a Diagnosis of Early Breast Cancer

作者：Belinda Thewes, Bettina Meiser, Alan Taylor, Kelly‐Anne Phillips, Sarah Tamsin Pendlebury, Anne Capp, David N. Dalley, David B Goldstein, Rod Baber, Michael Leonard Friedlander · 发表于：Journal of Clinical Oncology · 年份：2005 · DOI：10.1200/jco.2005.07.773 · 被引用次数：261 · 研究领域：Reproductive Biology and Fertility、Reproductive Health and Technologies、Cancer Risks and Factors

PURPOSE: The use of chemotherapy and endocrine therapies in the treatment of premenopausal women carries with it reproductive and gynecologic implications that young women may find distressing and discordant with plans for childbearing. This multicenter study aimed to investigate fertility- and menopause-related information needs among young women with a diagnosis of early-stage breast cancer. PATIENTS AND METHODS: Two hundred twenty-eight women with a diagnosis of early-stage breast cancer who were aged 40 years or younger at diagnosis and who were 6 to 60 months after diagnosis were entered onto the trial. Participants completed a mailed self-report questionnaire that included a purposely designed fertility- and menopause-related information needs survey and standardized measures of distress, anxiety, quality of life, menopausal symptoms, and information-seeking style. RESULTS: Seventy-one percent of participants discussed fertility-related issues with a health professional as part of their breast cancer treatment, and 86% discussed menopause-related issues. Consultation with a fertility or menopause specialist was the most preferred method of obtaining this information. Receiving fertility-related information was rated as being significantly more important than receiving menopause-related information at time of diagnosis (P < .001) and at treatment decision making (P = .058). Receiving menopause-related information was rated as being significantly more important than recei...