Inflammatory response to cardiopulmonary bypass

作者：L. Henry Edmunds · 发表于：The Annals of Thoracic Surgery · 年份：1998 · DOI：10.1016/s0003-4975(98)00967-9 · 被引用次数：339 · 研究领域：Cardiac and Coronary Surgery Techniques、Mechanical Circulatory Support Devices、Cardiac, Anesthesia and Surgical Outcomes

This article reviews the roles of the contact and complement systems and of neutrophils and monocytes in the inflammatory response to cardiopulmonary bypass and open heart operation. These blood proteins and cells, together with other blood elements, produce the vasoactive and cytotoxic substances and microemboli that cause the morbidity associated with cardiopulmonary bypass and open heart operation.