EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome

作者：Glenn E. Palomaki, Monica R. McClain, Stephanie N Melillo, Heather L. Hampel, Stephen N. Thibodeau · 发表于：Genetics in Medicine · 年份：2009 · DOI：10.1097/gim.0b013e31818fa2db · 被引用次数：471 · 研究领域：Genetic factors in colorectal cancer、Colorectal Cancer Screening and Detection、Cancer Genomics and Diagnostics

An original evidence review examined screening and diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) and the subsequent outcomes in a population of newly diagnosed cases of colorectal cancer (CRC). This supplementary evidence review focuses on five issues of further interest to the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group (EWG), as summarized below.