A rare case of eight multiple primary malignant neoplasms in a female patient: A case report and review of the literature

作者：Jiemin Zhao, Yan Tan, Yugang Wu, Wei Zhao, Jun Wu, Mei Ji, Liangrong Shi, Jingting Jiang, Changping Wu · 发表于：Oncology Letters · 年份：2014 · DOI：10.3892/ol.2014.2789 · 被引用次数：23 · 研究领域：Multiple and Secondary Primary Cancers、Genetic factors in colorectal cancer、Lung Cancer Treatments and Mutations

In recent years, the number of patients exhibiting multiple primary malignant neoplasms has been increasing. The current study reports the rare case of a 61-year-old Chinese female with eight histopathologically confirmed primary malignant neoplasms; to the best of our knowledge, such a high number of malignant neoplasms in one patient has not previously been described in the English literature. The tumors originated from the colon (five separate tumors over 32 years), the endometrium, the breast and the small intestine. It is important to diagnose multiple primary malignant neoplasms as such patients generally exhibit a more favorable prognosis compared with metastatic carcinoma patients. In addition, prolonged follow-up after surgery should be considered.