Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators

作者：Chuangxing Guo, Angelica Linton, Mehran Jalaie, Susan E. Kephart, Martha A. Ornelas, Mason Pairish, S.E. Greasley, Paul Richardson, Karen A. Maegley, Michael J. Hickey, John Li, Xin Wu, Ji X, Zhi Xie · 发表于：Bioorganic & Medicinal Chemistry Letters · 年份：2013 · DOI：10.1016/j.bmcl.2013.03.090 · 被引用次数：46 · 研究领域：Cancer, Hypoxia, and Metabolism、Biochemical and Molecular Research、Cancer therapeutics and mechanisms