Synthesis of the first nano ionic liquid 1-methylimidazolium trinitromethanide {[HMIM]C(NO 2 ) 3 } and its catalytic use for Hanztsch four-component condensation

作者：Mohammad Ali Zolfigol, Saeed Baghery, Ahmad Reza Moosavi‐Zare, Seyed Mohammad Vahdat, Heshmatollah Alinezhad, Mohammad Norouzi · 发表于：RSC Advances · 年份：2014 · DOI：10.1039/c4ra09117e · 被引用次数：54 · 研究领域：Ionic liquids properties and applications、Multicomponent Synthesis of Heterocycles、Synthesis and Biological Evaluation

A novel, green and reusable nano ionic liquid and catalyst, namely 1-methylimidazolium trinitromethanide {[HMIM]C(NO2)3}, was designed and fully characterized by 1H NMR, 13C NMR, IR, mass, X-ray diffraction patterns (XRD) and Transmission electron microscopy (TEM) analysis. The catalytic application of the presented catalyst was successfully tested on the Hantzsch four-component reaction of various aromatic aldehydes, 1,3-dione, β-ketoester and ammonium acetate at room temperature under solvent-free and mild conditions to give the polyhydroquinoline derivatives in good to excellent yields. In the presented work, some products have been reported for the first time.