Rothia dentocariosa sepsis in a pediatric renal transplant recipient having post‐transplant lymphoproliferative disorders

作者：Silke Wiesmayr, Ingrid Stelzmueller, Natalie Berger, Therese Jungraithmayr, Manfred Fille, M. Eller, Lothar Bernd Zimmerhackl, Raimund Margreiter, Hugo Bonatti · 发表于：Pediatric Transplantation · 年份：2006 · DOI：10.1111/j.1399-3046.2005.00472.x · 被引用次数：13 · 研究领域：Diphtheria, Corynebacterium, and Tetanus、Medicine and Dermatology Studies History、Mycobacterium research and diagnosis

BACKGROUND: Rothia dentocariosa (RD) is a Gram-positive rod that colonizes the human oral cavity and can cause infective endocarditis. RESULT: We report on a six-yr-old boy who underwent renal transplantation for polycystic kidney disease at the age of eight months. He developed post-transplant lymphoproliferative disorders after four yr and progressive graft failure. Following chemotherapy, the patient presented with neutropenia and sepsis. RD was isolated from blood and treatment with piperacillin/tazobactam was initiated; however, the child died because of multiorgan failure. DISCUSSION: To the best of our knowledge, this is the first case of RD sepsis in a pediatric solid organ transplant recipient.