Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

作者：Eric S. Fischer, Kerstin Böhm, John R. Lydeard, Haidi Yang, Michael Stadler, Simone Cavadini, Jane Nagel, Fabrizio C. Serluca, Vincent Acker, Gondichatnahalli M. Lingaraju, Ritesh B. Tichkule, Michael Schebesta, William C. Forrester, Markus Schirle, Ulrich Hassiepen, Johannes Ottl, Marc Hild, Rohan E. J. Beckwith, J. Wade Harper, Jeremy L. Jenkins, Nicolas H. Thomä · 发表于：Nature · 年份：2014 · DOI：10.1038/nature13527 · 被引用次数：1125 · 研究领域：Protein Degradation and Inhibitors、Multiple Myeloma Research and Treatments、Ubiquitin and proteasome pathways