Hematopoietic Stem-Cell Transplantation

作者：Edward Alan Copelan · 发表于：New England Journal of Medicine · 年份：2006 · DOI：10.1056/nejmra052638 · 被引用次数：2522 · 研究领域：Hematopoietic Stem Cell Transplantation、Acute Lymphoblastic Leukemia research、Acute Myeloid Leukemia Research

Hematopoietic stem-cell transplantation, which is used to treat both malignant and nonmalignant conditions, was first conceived more than 50 years ago, but problems associated with transplanting a nonsolid organ and modulating the immune response had to be solved before the procedure could be used clinically. This review summarizes background information about hematopoietic stem-cell transplantation and discusses the current role of the procedure.