Isolation and partial characterization of the human homologue of Thy-1.

作者：Edwin W. Ades, Robert K. Zwerner, Ronald T. Acton, Charles M. Balch · 发表于：The Journal of Experimental Medicine · 年份：1980 · DOI：10.1084/jem.151.2.400 · 被引用次数：63 · 研究领域：Toxin Mechanisms and Immunotoxins、Glycosylation and Glycoproteins Research、Natural product bioactivities and synthesis

A glycoprotein of 25,000 daltons was isolated from a human T lymphoblastoid cell line (MOLT-3). A monovalent antiserum raised against this antigen precipitated mouse Thy-1.1 antigen as well as a 25,000-dalton antigen from human blood T cells. The unabsorbed serum was also cytotoxic for both mouse and human T cells. By multiple criteria, this human T antigen appears to be homologous with mouse Thy-1.