Comparative Activities of Clinafloxacin, Grepafloxacin, Levofloxacin, Moxifloxacin, Ofloxacin, Sparfloxacin, and Trovafloxacin and Nonquinolones Linozelid, Quinupristin-Dalfopristin, Gentamicin, and Vancomycin against Clinical Isolates of Ciprofloxacin-Resistant and -Susceptible Staphylococcus aureus Strains

作者：Mark E. Jones, Maarten R. Visser, Miriam Klootwijk, Peter Heisig, J. Verhoef, Franz‐Josef Schmitz · 发表于：Antimicrobial Agents and Chemotherapy · 年份：1999 · DOI：10.1128/aac.43.2.421 · 被引用次数：89 · 研究领域：Antimicrobial Resistance in Staphylococcus、Ocular Infections and Treatments、Bacterial Identification and Susceptibility Testing

The activities of eight fluoroquinolones and linezolid, quinupristin-dalfopristin (Synercid), gentamicin, and vancomycin were tested against 96 ciprofloxacin-susceptible and 205 ciprofloxacin-resistant Staphylococcus aureus strains. Overall, clinafloxacin, followed by moxifloxacin and trovafloxacin, was the most active quinolone tested. For all isolates, linezolid and quinupristin-dalfopristin showed activities that were at least comparable to vancomycin, with no cross-resistance to any other test compound.