Postoperative Intraspinal Subdural Collections after Pediatric Posterior Fossa Tumor Resection: Incidence, Imaging, and Clinical Features

作者：Julie H. Harreld, N. Mohammed, Geoffrey Goldsberry, Xiaofei Li, Yujun Li, Frederick A. Boop, Zoltán Patay · 发表于：American Journal of Neuroradiology · 年份：2015 · DOI：10.3174/ajnr.a4221 · 被引用次数：19 · 研究领域：Glioma Diagnosis and Treatment、Management of metastatic bone disease、Neurosurgical Procedures and Complications

BACKGROUND AND PURPOSE: Postoperative intraspinal subdural collections in children after posterior fossa tumor resection may temporarily hinder metastasis detection by MR imaging or CSF analysis, potentially impacting therapy. We investigated the incidence, imaging and clinical features, predisposing factors, and time course of these collections after posterior fossa tumor resection. MATERIALS AND METHODS: Retrospective review of postoperative spine MRI in 243 children (5.5 ± 4.6 years of age) from our clinical data base postresection of posterior fossa tumors from October 1994 to August 2010 yielded 37 (6.0 ± 4.8 years of age) subjects positive for postoperative intraspinal subdural collections. Their extent and signal properties were recorded for postoperative (37/37), preoperative (15/37), and follow-up spine (35/37) MRI. Risk factors were compared with age-matched internal controls (n = 37, 5.9 ± 4.5 years of age). Associations of histology, hydrocephalus and cerebellar tonsillar herniation, and postoperative intracranial subdural collections with postoperative intraspinal subdural collections were assessed by the Fisher exact test or χ(2) test. The association between preoperative tumor volume and postoperative intraspinal subdural collections was assessed by the Wilcoxon rank sum test. RESULTS: The overall incidence of postoperative intraspinal subdural collections was 37/243 (15.2%), greatest ≤7 days postoperatively (36%); 97% were seen 0-41 days postoperatively (12.9 ...