PlantQTL-GE: a database system for identifying candidate genes in rice and Arabidopsis by gene expression and QTL information

作者：Hengxi Zeng, Lijun Luo, Weixiong Zhang, Jun Zhou, Ziwei Li, H. Liu, Tong Zhu, Xiao Feng, Yi Zhong · 发表于：Nucleic Acids Research · 年份：2006 · DOI：10.1093/nar/gkl814 · 被引用次数：25 · 研究领域：Genetic Mapping and Diversity in Plants and Animals、Genomics and Phylogenetic Studies、Plant nutrient uptake and metabolism

We have designed and implemented a web-based database system, called PlantQTL-GE, to facilitate quantitatine traits locus (QTL) based candidate gene identification and gene function analysis. We collected a large number of genes, gene expression information in microarray data and expressed sequence tags (ESTs) and genetic markers from multiple sources of Oryza sativa and Arabidopsis thaliana. The system integrates these diverse data sources and has a uniform web interface for easy access. It supports QTL queries specifying QTL marker intervals or genomic loci, and displays, on rice or Arabidopsis genome, known genes, microarray data, ESTs and candidate genes and similar putative genes in the other plant. Candidate genes in QTL intervals are further annotated based on matching ESTs, microarray gene expression data and cis-elements in regulatory sequences. The system is freely available at http://www.scbit.org/qtl2gene/new/.