A randomised, double-blind, placebo-controlled trial of trametinib, an oral MEK inhibitor, in combination with gemcitabine for patients with untreated metastatic adenocarcinoma of the pancreas

作者：Jeffrey R. Infante, Bradley G. Somer, Joon Oh Park, Chung‐Pin Li, Max Ernst Scheulen, Saifuddin M. Kasubhai, Do‐Youn Oh, Yuan Liu, Suman Redhu, Klaudia M. Steplewski, Ngocdiep T. Le · 发表于：European Journal of Cancer · 年份：2014 · DOI：10.1016/j.ejca.2014.04.024 · 被引用次数：376 · 研究领域：Pancreatic and Hepatic Oncology Research、Melanoma and MAPK Pathways、FOXO transcription factor regulation