Capillary Electrophoretic Behaviors of Pharmacologically Active Xanthones from Securidaca inappendiculata with  -Cyclodextrin as a Buffer Additive

作者：Tao Bo, Yan Huang, Xinyi Yang, Kepiao Li, Hongbo Liu, Lai Xu · 发表于：Journal of Chromatographic Science · 年份：2003 · DOI：10.1093/chromsci/41.4.182 · 被引用次数：7 · 研究领域：Natural Compound Pharmacology Studies、Polysaccharides and Plant Cell Walls、Phytochemicals and Antioxidant Activities

The capillary electrophoretic (CE) behaviors of ten xanthones in the presence of beta-cyclodextrin (CD) are investigated, and apparent analyte-selector binding constants between beta-CD and the xanthones in the CE running buffer are calculated to elucidate the migration order. Also, the separation selectivity with beta-CD additive is compared with that of sulfated beta-CD additive. It is indicated that beta-CD can greatly change the separation selectivity of xanthones, and the electrophoretic behaviors of xanthones are rather different when using beta-CD from that when using sulfated beta-CD as an additive.