Non-Hodgkin's Lymphoma of Mucosa-Associated Lymphoid Tissue

作者：Seth M. Cohen, Magdalena Petryk, Mala Varma, Peter Kozuch, Elizabeth D. Ames, Michael L. Grossbard · 发表于：The Oncologist · 年份：2006 · DOI：10.1634/theoncologist.11-10-1100 · 被引用次数：95 · 研究领域：Lymphoma Diagnosis and Treatment、Genetic factors in colorectal cancer、Colorectal Cancer Treatments and Studies

Abstract Learning Objectives After completing this course, the reader will be able to: Outline the definition and classification of MALT lymphoma.Summarize the current understanding of the pathogenesis of MALT lymphoma.Articulate treatment options for patients with MALT lymphoma. Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.com The concept of mucosa-associated lymphoid tissue (MALT) lymphomas was introduced by Isaacson and Wright [Cancer 1983; 52:1410–1416] in 1983. After more than 20 years of clinical research MALT lymphomas are now recognized as a distinct subtype of non-Hodgkin's lymphoma (NHL) with unique pathogenic, histological, and clinical features. Although this subtype of NHL occurs frequently, optimal management remains elusive. This manuscript reviews features of the clinical presentation, diagnosis, pathology, molecular characteristics, and management of both gastric and non-gastric MALT lymphoma.