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A comprehensive review of glycosylated bacterial natural products

作者:Sherif I. Elshahawi, Khaled A. Shaaban, Madan K. Kharel, Jon S. Thorson · 发表于:Chemical Society Reviews · 年份:2015 · DOI:10.1039/c4cs00426d · 被引用次数:452 · 研究领域:Microbial Natural Products and Biosynthesis、Enzyme Production and Characterization、Carbohydrate Chemistry and Synthesis

A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites reported in the scientific literature up through early 2013 is presented. This comprehensive analysis of 15 940 bacterial natural products revealed 3426 glycosides containing 344 distinct appended carbohydrates and highlights a range of unique opportunities for future biosynthetic study and glycodiversification efforts.