Intermediate Filaments: Conformity and Diversity of Expression and Structure

作者：Peter M. Steinert, David A.D. Parry · 发表于：Annual Review of Cell Biology · 年份：1985 · DOI：10.1146/annurev.cb.01.110185.000353 · 被引用次数：244 · 研究领域：DNA and Nucleic Acid Chemistry、thermodynamics and calorimetric analyses

INTRODUCTION: INTERMEDIATE FILAMENTS ARE UBIQUITOUS .......• ••.........• 42 SUBUNIT STRUCTURE •.......•••.......••......••.••...••.••......•••••...•••.••......••......•••......••.•.......••.......••.•.......•.........•. 43 General F eatures 43 N omenc/ature 43 Structural Features of the IX-Helical Rod Domain 47 Structural Features of the End Domains 48 MODELS FOR IF STRUCTURE .....••......•...••.....••.......•••.......•••......•••......••..•......•.......••.•.......••.......• •• 49 The Two-Chain Coiled-Coil Molecule 49 The Fundamental Four-Chain Coiled-Coil Unit of All IF 50 Possibilities for Packing of Four-Chain Units within IF 51 Peripheral Locations of Functional End Domains 56