Self‐assembling amphiphilic peptides

作者：Ashkan Dehsorkhi, Valeria Castelletto, Ian William Hamley · 发表于：Journal of Peptide Science · 年份：2014 · DOI：10.1002/psc.2633 · 被引用次数：391 · 研究领域：Supramolecular Self-Assembly in Materials、Chemical Synthesis and Analysis、Polydiacetylene-based materials and applications

The self-assembly of several classes of amphiphilic peptides is reviewed, and selected applications are discussed. We discuss recent work on the self-assembly of lipopeptides, surfactant-like peptides and amyloid peptides derived from the amyloid-β peptide. The influence of environmental variables such as pH and temperature on aggregate nanostructure is discussed. Enzyme-induced remodelling due to peptide cleavage and nanostructure control through photocleavage or photo-cross-linking are also considered. Lastly, selected applications of amphiphilic peptides in biomedicine and materials science are outlined.