Prevalence of Epilepsy in Rochester, Minnesota: 1940–1980

作者：W. Allen Hauser, John Fred Annegers, Leonard T. Kurland · 发表于：Epilepsia · 年份：1991 · DOI：10.1111/j.1528-1157.1991.tb04675.x · 被引用次数：852 · 研究领域：Epilepsy research and treatment、Pharmacological Effects and Toxicity Studies、Metabolism and Genetic Disorders

Summary: : The prevalence of epilepsy in Rochester, Minnesota has been determined for a specific date in each of 5 decennial census years. Individuals with a diagnosis of epilepsy (recurrent unprovoked seizures) who were known to have experienced a seizure or who had received antiepileptic medication in the preceding 5 years were considered active prevalence cases. By this definition, the age‐adjusted prevalence per 1,000 population, increased steadily from 2.7 in 1940 to 6.8 in 1980. At each of five prevalence dates, for all prevalence cases, 60% had epilepsy manifest by partial seizures, and 75% had no known etiology. Prevalence was higher for males than females for all except the last prevalence day. After 1950, prevalence tended to increase with advancing age and was highest in the oldest age groups. On the average, the 1980 prevalence cases had epilepsy <10 years and >50% had their first diagnosis in the first 20 years of life. RÉSUMÉ La prévalence de ľ epilepsie dans le Comtéde Rochester, dans le Minnesota, a étéévaluée pour une date precise de chacune des 5 années du recensement décennal. Les individus pour lesquels le diagnostic ďepilepsie avait été posé (crises spontanées récurrentes) et qui avaient présenté une crise ou recevaient un traitement antiépileptiques dans les 5 années précédentes, ont été considérés comme des cas de prévalence active. Selon cette définition, la prévalence ajustée pour Page pour 1000 habitants a agumenté constamment de 2.7 en 1940 à 6.8 en...