Rapid Detection of Carbapenemase-producing Enterobacteriaceae

作者：Patrice Nordmann, Laurent Poirel, Laurent Dortet · 发表于：Emerging infectious diseases · 年份：2012 · DOI：10.3201/eid1809.120355 · 被引用次数：771 · 研究领域：Antibiotic Resistance in Bacteria、Enterobacteriaceae and Cronobacter Research、Pharmaceutical and Antibiotic Environmental Impacts

To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem. It was 100% sensitive and specific compared with molecular-based techniques. This rapid (<2 hours), inexpensive technique may be implemented in any laboratory.