Determinants of Mortality at Older Ages: The Role of Biological Markers of Chronic Disease

作者：Cássio M. Turra, Noreen Goldman, Christopher L. Seplaki, Dana A. Glei, Yu‐Hsuan Lin, Maxine Weinstein · 发表于：Population and Development Review · 年份：2005 · DOI：10.1111/j.1728-4457.2005.00093.x · 被引用次数：29 · 研究领域：Health disparities and outcomes、Birth, Development, and Health、Optimism, Hope, and Well-being

Researchers have had a longstanding interest in understanding the determinants of mortality. This article examines the impact of a broad array of biological markers, together with self-reports of physical and mental health status, on the probability of dying for older adults. The estimates are derived from logistic regression models based on data from a national survey in Taiwan. The analysis confirms previous studies demonstrating the effects of clinical measures related to metabolic syndrome on mortality and identifies detrimental effects of neuroendocrine and immune-system markers. The results reveal that biomarkers provide independent explanatory power in the presence of self-reported health measures. The associations between biomarkers and mortality found here provide new avenues for projecting future mortality and elucidating differences in longevity across populations.