Bacterial Cell Division Regulation: Characterization of the dnaH Locus of Escherichia coli

作者：Camille C. Filip, Jane Smith Allen, Ralph A. Gustafson, Robert G. Allen, James R. Walker · 发表于：Journal of Bacteriology · 年份：1974 · DOI：10.1128/jb.119.2.443-449.1974 · 被引用次数：81 · 研究领域：DNA and Nucleic Acid Chemistry、Bacterial Genetics and Biotechnology、DNA Repair Mechanisms

The dnaH locus is the fourth gene to be identified as required for deoxyribonucleic acid polymerization in Escherichia coli. A temperature-sensitive mutant defective in this gene exhibited an abrupt decrease in rate of deoxyribonucleic acid synthesis when shifted to 42 C. The locus mapped in the proC-purE region of the chromosome by conjugation and was co-transducible with purE. dnaH(+) is carried on the F'(13) episome and is dominant over the dnaH(-) mutation.