Oriented crystallization of hydroxyapatite by the biomimetic amelogenin nanospheres from self-assemblies of amphiphilic dendrons

作者：Sheng Yang, Hai He, Lei Wang, Xinru Jia, Hailan Feng · 发表于：Chemical Communications · 年份：2011 · DOI：10.1039/c1cc13661e · 被引用次数：56 · 研究领域：Bone and Dental Protein Studies、Bone Tissue Engineering Materials、Dental materials and restorations

An amphiphilic PAMAM dendron with aspartic acids on the periphery and an aliphatic chain at the focal point was synthesized. The dendrons initially self-assembled to nanospheres in aqueous solution and further translated to linear chains that showed a function similar to amelogenin in the oriented growth of HAP in vitro.