Further characterization of borderline methicillin-resistant Staphylococcus aureus and analysis of penicillin-binding proteins

作者：Maria Pia Montanari, Elena Tonin, Francesca Biavasco, Pietro Emanuele Varaldo · 发表于：Antimicrobial Agents and Chemotherapy · 年份：1990 · DOI：10.1128/aac.34.5.911 · 被引用次数：67 · 研究领域：Antimicrobial Resistance in Staphylococcus、Antibiotic Resistance in Bacteria、Bacterial biofilms and quorum sensing

Eighty-nine Staphylococcus aureus strains were grouped according to their susceptibility or resistance to methicillin and oxacillin. The role of beta-lactamase in borderline methicillin resistance was confirmed by tests with beta-lactamase inhibitors, particularly when salt-supplemented medium was used. A penicillin-binding protein assay indicated that borderline methicillin-resistant S. aureus strains do not produce PBP 2a.