Toward Rapid, “Green”, Predictable Microwave-Assisted Synthesis

作者：B.A. Roberts, Christopher Roy Strauss · 发表于：Accounts of Chemical Research · 年份：2005 · DOI：10.1021/ar040278m · 被引用次数：429 · 研究领域：Microwave-Assisted Synthesis and Applications、Multicomponent Synthesis of Heterocycles、Catalysis for Biomass Conversion

Continuous and batch microwave reactors were constructed for efficient, "green" synthesis with low-boiling solvents at high temperature in closed vessels. Capabilities for rapid heating and cooling, concurrent heating and cooling, and differential heating facilitated novel chemical reactions and processes. Commercial microwave systems based on these developments are available. Times required for conventional reactions typically are decreased by 2-3 orders of magnitude. Green processes also have resulted through use of less or no catalyst, readily recyclable solvents, or media and yields that are often higher than normal. Complementary interactive software for calculating optimal conditions was developed.