SOME EFFECTS OF RESTRICTION OF CHEST CAGE EXPANSION ON PULMONARY FUNCTION IN MAN: AN EXPERIMENTAL STUDY*†

作者：Colin G. Caro, John Butler, Arthur B. DuBois · 发表于：Journal of Clinical Investigation · 年份：1960 · DOI：10.1172/jci104070 · 被引用次数：235 · 研究领域：Respiratory Support and Mechanisms

Certain alterations in pulmonary mechanics occur in man when an inspiration is taken from below the resting lung volume (1) and during shallow breathing (2). Some effects of a sustained reduction of the total lung capacity on respiration have been studied previously (3-5), yet the effects of chest strapping on pulmonary mechanics have received relatively little attention. In the preliminary experiments we tightly bound the chest in the expiratory position with either adhesive tape or a long strip of rubber. Subsequently we designed a special chest corset that permitted us to reduce the resting lung volume and inspiratory capacity at will. The entire pressure-volume curve of the lung was altered by these procedures, but was restored to normal when a deep inspiration was taken after release of the restricting apparatus. Simultaneously, the escape of gas from poorly ventilated regions of the lung was detected. The effect of these changes on other aspects of pulmonary and circulatory function was examined and our findings, together with a consideration of their physiological and clinical significance, form the basis of this report.