Prognosis research strategy (PROGRESS) 4: Stratified medicine research

作者：Aroon D. Hingorani, Daniëlle van der Windt, Richard D Riley, Keith R. Abrams, Karel Moons, Ewout W. Steyerberg, Sara Schroter, Willi Sauerbrei, Doug Altman, Harry Hemingway, for the PROGRESS Group · 发表于：BMJ · 年份：2013 · DOI：10.1136/bmj.e5793 · 被引用次数：526 · 研究领域：Health Systems, Economic Evaluations, Quality of Life、Statistical Methods in Clinical Trials、Meta-analysis and systematic reviews

In patients with a particular disease or health condition, stratified medicine seeks to identify those who will have the most clinical benefit or least harm from a specific treatment. In this article, the fourth in the PROGRESS series, the authors discuss why prognosis research should form a cornerstone of stratified medicine, especially in regard to the identification of factors that predict individual treatment response