Endocrine tumour in kidney affecting small bowel structure, motility, and absorptive function

作者：Michael Gleeson, S.R. Bloom, Julia M. Polak, Kathleen Mary Henry, R. H. Dowling · 发表于：Gut · 年份：1971 · DOI：10.1136/gut.12.10.773 · 被引用次数：382 · 研究领域：Neuroendocrine Tumor Research Advances、Diet and metabolism studies、Ion Transport and Channel Regulation

A 44-year-old woman is described with an endocrine tumour arising in the kidney. There were associated abnormalities of small intestinal morphology, motility, and absorptive function. These abnormalities reversed on removal of the tumour. Detailed studies showed that the tumour contained, and was secreting, glucagon. It is postulated that the intestinal abnormalities may have resulted from glucagon itself or another, as yet unidentified, hormone.