A Synergistically Enhanced T1–T2 Dual‐Modal Contrast Agent

作者：Zijian Zhou, Dengtong Huang, Jianfeng Bao, Qiaoli Chen, Gang Liu, Zhong Chen, Xiaoyuan Chen, Jinhao Gao · 发表于：Advanced Materials · 年份：2012 · DOI：10.1002/adma.201203169 · 被引用次数：293 · 研究领域：Nanoparticle-Based Drug Delivery、Characterization and Applications of Magnetic Nanoparticles、Nanoplatforms for cancer theranostics

Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1) and T(2) effects. GdIO nanoparticles have the unique property to be both T(1) and T(2) contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.