Does Polycystic Ovary Syndrome Itself Have Additional Effect on Apelin Levels?
作者:Dilek Benk Şilfeler, Cumali Gökçe, Raziye Keskin Kurt, Nigar Yilmaz Atilgan, Oktay Hasan Öztürk, Ebru Turhan, Ali Baloğlu · 发表于:Obstetrics and Gynecology International · 年份:2014 · DOI:10.1155/2014/536896 · 被引用次数:16 · 研究领域:Apelin-related biomedical research、Lipid metabolism and disorders、Paraoxonase enzyme and polymorphisms
Objective. The present study was designed to compare serum levels of apelin between lean PCOS women and healthy women with regular menses. Study Design. A total of 30 lean patients with PCOS and 30 healthy subjects were included in this study. Serum apelin levels were compared between groups. Results. Serum apelin levels in lean PCOS patients were not significantly different from the control subjects. Conclusion. Our findings indicate that PCOS itself does not seem to change apelin levels. Further investigation on a large number of subjects will need to be conducted to prove the consistent or variable association in PCOS.